The vaccination against Parvo, Distemper and Hepatitis are nearly 100% effective. In 20 years, I’ve seen one fully vaccinated dog develop a parvovirus infection. Every other case I have ever seen has occurred in unvaccinated or under-vaccinated dogs.
Canine Cough vaccines are less effective, but if the dog does contract the condition we find it is much less severe and affects the dog for a much shorter period of time.